How about Cassowary, with size classes?
I spend half my programming time working on Mac software and half on web software, and I find element layout in the former is infinitely more pleasant. No need to put elements in a specific place in the document structure to lay them out the way I want. No need to change how I'm working for vertical versus horizontal layout. Just pick the dimension/coordinate you want to set, pick the other dimension/coordinate you want it to maintain its proportion to, and you're done.
Apple's implementation got a bad rap, I believe, because the first version of Xcode didn't support it well, the first version of the API was a terrible fit for Swift (which came a couple years after it), and pre-Sierra macOS had a lot of bugs in the implementation. Today, there's no layout system I'd rather use.