I'm language agnostic, I don't care much about them, I just wants to get things done. Red have features that ease things like its unique parse engine
https://redlang.red/parse-html which avoid regex headache (recently javascript recognized the problem and tried to add methods to ease parsing it's far from being as elegant as red. I don't remember the research paper from which Carl Sessenrath inspired fromn but it is clearly closer to natural language processing, though still not close enough in my opinion so I'm working on making a dialect that would almost feel the gap and allows anybody to create its own AI for example ;)
So at this stage for me, Red being in alpha stage (not even 1.0. yet and roadmap goes up to 2), you cannot use it like you would use nodejs. Tcp/ip has just being implemented, I hope to have something like async nodejs https server and an independant framework similar to express instead of full blown monolitic server but I don't know what the future will be.
But it is very usable for meta-programming stuff. readable.red is only one brick, I have other projects which will use red to generate code easily in other programming languages in much more friendly way that traditional DSL made for PHD people only ;)