I've measured the exact point at which an object leaves the field of vision of the side mirror, and I'm pretty sure it's slightly ahead of the driver side window, at which point glancing at the mirror will see them anyway. There's potentially a blind spot if a motorcyclist or bicyclist is on the far side of the lane next to you (not close to the car, but lined up with it), but as long as you change lanes slowly and don't just barrel across 4 lanes of traffic you'll see them long before you hit them.