I guess, you could also argue that in the east coast, people are less friendly, so you have fewer friends and people have to keep them closer and dearly, or that in SF there is a lot of stuff to do, and people can get easily ditracted.
BTW. I am european, so don't want to transform this in a west coast vs. east coast thing.
When it comes to twitter, I am not sure how much the general crowd would be interested in it. Taking example something like blogs: it has instant appeal in a lot of people, because basically it is an online diary.
A lot of people have diaries, and bringing them online was something natural.
But twitter? I am not sure it solves a need to the general masses, except for the hyperconnected ones.