Constant Contact is the one I use and offer to my clients. The main reason is I personally get a higher delivery rate (instead of getting caught in spam filters) and their email creator wizard is awesome. Try out their 60-day free trial:
http://email.volcanicmarketing.comOther solutions out there are:
* iContact http://www.icontact.com - Their customer service sucked when I tried them out.
* Campaign Monitor http://www.campaignmonitor.com - I've heard good things about their reports but their delivery rates have not been as great as Constant Contact in my email campaigns.
* Exact Target http://www.exacttarget.com - Great for enterprise companies. They will cost at least $10k/year
* Vertical Response http://www.VerticalResponse.com
* SilverPOP http://www.silverpop.com Another enterprise solution with a big cost.