I don't think Luddites are savvy enough to figure out how to disable JavaScript, and most of the people who disable JavaScript are probably at the opposite end of the spectrum: people who know the privacy and security risks of JavaScript, and who would rather a website be obviously broken on the first visit than have it be subversively annoying and ad-laden.
If an e-commerce site won't let me get to their product list and see prices without cookies and Javascript, I won't buy from them if there are alternatives. There's no real justification for making a simple online store 100% AJAX for even the most basic features, so the sites that do that don't get my money. (They probably don't do to well from an SEO perspective, either.)
Blogs that require cookies and JavaScript before they'll show their content are obviously more concerned with spamming me than being of use to me, so they also get closed immediately.