I've been using Macs as my development machines since before Darwin became OSX and that's the only thing that frustrates me sometimes: decent package/library management like on Linux. I've resorted to isolating these issues in VMs running Linux. Anyone else has a better approach? Do you --PREFIX everything you compile? This can be particularly painful for academic software: this type of soft has the annoying tendency to become abandonware the second the Phd thesis is written or publication has been accepted.