Not sure how you intended this, but the hero pool constraint is actually an enormous advantage for the AI. The current hero pool isn't, by any means, random. I don't know OpenAI selected it, but it's highly conducive to OpenAI Five's strengths--deathballing, mechanics, teamfight coordination, etc. It lacks essentially all of the heroes that humans would normally pick to counter that strategy.
Playing on an unrestricted hero set would test OpenAI Five in entirely different ways than playing on the current hero pool would. I would not be comfortable betting on your statement at all.