Not according to Augery (angular chrome extension), but not sure if all evidence can be built out of the result.
However, mobile.twitter.com and facebook proper are using react. Along with Walmart.com and many, many others.
The biggest Angular app I've seen is probably grubhub, and there's some painful state bugs there... in fact I don't think I've ever seen an angular app (not using rxjs or redux) that doesn't have weird state management bugs.
