> industrial quality VM+JIT
I'll skip over this mostly, just wondering what exactly you mean about this and whether you consider LLVM not to be "industrial quality" seeing as the failed Unladen Swallow project based itself upon that and it didn't seem to get them anywhere.
> it's primary goal is being compatible with the Scipy ecosystem at least
Well... it's not like PyPy isn't "compatible" with the scipy ecosystem. It just has to use a lower-performing object access mode to use cpyext-based extensions, which I suspect is a compromise any JIT-based implementation will need to make to be able to make use of these more old-school extensions.
Ironically on the subject of "industrial quality" JITs, GraalVM is based upon the same meta-tracing interpreter ideas that were largely pioneered by PyPy.