Although Scuttlebutt is a nice solution, I think it fails to replace Facebook because:
1. Different use case: trying it out it reminded me more of a Slack/IRC/bulletin board than anything else.
2. Different framing: it uses a public square (Twitter) framing (follow, follower, channel) instead of a personal relationships framing (friends, groups, etc).
3. Too complex for casual users: this is kind of ironic because Scuttlebutt is modeled after real life interactions but in a way it ends being too complex with pubs (public and private), long and cryptic user IDs, etc.
These are some reasons but there are more. Happy to discuss them.