If you have to apply to 250+ jobs just to get one, you can't invest much effort into each application.
I've been a part-time developer for three years (and worked full-time on top of that), and I'm looking for a full-time position. I gave up on tech after applying to 500+ jobs and getting three interviews and zero offers. The closest I got was a consulting outfit in a small city in the Inland North, where one of the interviewers got hostile about my major (philosophy) and eventually rejected me over it.
But even now that I'm only applying for positions that just need warm bodies with degrees, my ratio of applications to phone screens is upwards of twenty to one, and every phone screen I've gotten in the last month has rescheduled last-minute on me, sometimes more than once. And I have to put up with shit like getting rejected at the door because the interviewer doesn't like my [perfectly ordinary and unremarkable] shoes.
How in the world am I supposed to find the time to put effort into applying for hundreds of jobs?