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0 pointsAllegedAlec8y ago0 comments

Sure. It's still a game of chance. However, evolution is not random in the purest sense. Evolution itself skews the distribution of the kind of mutations you see.

For example: on of the papers by the Lenski labs show that the lambda phage evolves a certain defense mechanism very reliably in duplicated studies, despite it requiring several very specific mutations.

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Retric8y ago

Random does not mean a uniform distribution. Toss 2 six sided dice and 2's and 12's are uncommon. But it's still a random process.

Also, saying you often get some set of mutations may be likely if subsets of those mutations provide advantages or there is some process that makes those mutations more likely.

AllegedAlecOP8y ago

> Random does not mean a uniform distribution. Toss 2 six sided dice and 2's and 12's are uncommon. But it's still a random process.

True, but dice don't adjust their own shape so that they're more likely to stop at certain values.

> Also, saying you often get some set of mutations may be likely if subsets of those mutations provide advantages or there is some process that makes those mutations more likely.

Yeah, but doesn't take away from the fact that evolution is canalised into certain options (most of the time) by its own evolutionary history.

Retric8y ago

I am not disagreeing with that. I am simply saying even if 95% of the time you see a small set of options the other 5% get's increasingly bizarre. Start grouping them and the last 0.001% case has just about anything.

So, sure you can specify odds, but again that's very different than saying something is not random and thus predictable.

PS: I tend to focus on black swan events because they tend to be more important. If you focus on the most likely outcome that becomes less important over time. M1 - M10,000 might each be happy paths, but M1 - M10,000 is is extremely unlikely to have all of them be happy paths.

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Retric8y ago

Random does not mean a uniform distribution. Toss 2 six sided dice and 2's and 12's are uncommon. But it's still a random process.

Also, saying you often get some set of mutations may be likely if subsets of those mutations provide advantages or there is some process that makes those mutations more likely.

AllegedAlecOP8y ago

> Random does not mean a uniform distribution. Toss 2 six sided dice and 2's and 12's are uncommon. But it's still a random process.

True, but dice don't adjust their own shape so that they're more likely to stop at certain values.

> Also, saying you often get some set of mutations may be likely if subsets of those mutations provide advantages or there is some process that makes those mutations more likely.

Yeah, but doesn't take away from the fact that evolution is canalised into certain options (most of the time) by its own evolutionary history.

Retric8y ago

So, sure you can specify odds, but again that's very different than saying something is not random and thus predictable.

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