I’d say it’s the opposite as an die hard tmux-user. I don’t really use the integration since I’m more comfortable with my terminal in full screen and my own tmux config. The integration services seems more appropriate for someone who doesn’t already have their tmux-bindings and workflow stamped into muscle memory but rather just want the benefits of detaching their terminal sessions from their terminal application while retaining iterm native tabs, windows and panes.
I’ve tried out the integration mode a few times but it just doesn’t fit my workflow (often switching sessions, highly customized tmux configuration, etc).