Giving up the capabilities of the Saturn V hurt and cost every other project there after.
Look at the Space Station. It was way way more expensive because it had to be assembled in lots of flights.
The same goes for some of the deep space probs and space telescopes, they had to be designed often limited by small rockets.
Giving up the Saturn V was the biggest mistake the US Space program ever made. We are still working under that mistake and now have 3 groups trying to finally achieve something like it again, SLS, BFR, New Armstrong.