It will also help if you understand the chemistry of carbohydrates vs fats. Carbohydrates are inherently unstable and are much more likely to undergo spontaneous reactions than fats. This is because sugars are fringed with electrophyllic hydroxyl groups that will take part in dehydration reactions under physiological conditions. The result of this is advanced glycation end (AGE) products. The phytonutrients from plants seem to stabilize carbohydrates, which is probably part the reason the plant made them in the first place.
Carbohydrates aren't so much you body's preferred fuel, rather your body uses them first because letting them float around in circulation is harmful. This is particularly true of fructose, which the liver works very hard to prevent from entering general circulation.
> "In conclusion, macronutrient composition of the diet may differentially alter the postprandial pro-oxidative milieu, with high-carbohydrate meals potentially leading to greater oxidative stress response. However, both meals increased circulating IL6, regardless of the type of nutrient consumed."
I don't see how that translates into a sentence like your:
"Carbohydrates aren't so much you body's preferred fuel".
If you can connect the dots clearly I'd love to see it, but the impression I get is people like yourself and the 'inflammation' crowd are taking these very specific studies and totally distorting their meaning to make broader truths.
I tried to connect the dots a bit with some of the biochemistry of why carbohydrates need to be cleared quickly, it can't simplified much past that. What it comes down to is that oxygen atoms make molecules more chemically reactive than other common elements like carbon and nitrogen. This causes "unintended" reactions, which produce molecules the body doesn't know how to handle. These molecules can directly trigger an immune response, or they can be incorporated into other molecules which causes them to malfunction in various ways. Both cases are bad.
It isn't necessarily the inflammation itself that is bad. Rather, it is a sign that something is going wrong with your body. Usually when inflammation is high, either you have something foreign in your body, or your cells are killing themselves for some reason, and immune cells are being activated to "clean up" the debris.
