This is not true.
We have only two variadic special forms: "for" and "with".
"for" needs to be implemented as a special form as it emits some optimizations that are only available at the Core Erlang level.
"with" needs to be implemented as a special form as it has different lexical properties than a bunch of nested cases.
None of those could be implemented with macros.
Regarding whitespace sensitiveness, most languages have subtle issues, to varying degrees but especially if you have optional line terminators. Although it is true one or two extra cases appear in Elixir due to optional parentheses.