From what I've seen, the difference between Python 2.x and 3.x is tiny compared to the Perl 5/6 change.
The difference between Perl 5 and Perl 6 is probably about 10x the difference between Perl 5.10 and 5.26
I like to explain it this way:
Perl 4 is to C
as Perl 5 is to C++
as Perl 6 is to Haskell/Smalltalk/C#/Swift/Julia…
So I might agree actually on the "bigger", but the "noticeability" does have a lot to do with the general feeling.
(to be clear, I agree with all of your comment)
From what I know about Python 2/3, it's that you can write maybe 90% on average/in general of your code the same way without much thought about the differences. However, if you do wish to adopt the new features, there's plenty to keep you busy writing scripts for at least a few months, maybe even a year.
It's basically a different language that shares some things, with few users. It would be nice to see it shopped, but you might as likely wish distribution shipped with crystal or nim.
$ cat /etc/redhat-release
CentOS Linux release 7.3.1611 (Core)
$ yum info rakudo
Loaded plugins: fastestmirror
Loading mirror speeds from cached hostfile
* base: mirror.team-cymru.org
* epel: mirror.oss.ou.edu
* extras: mirror.cloud-bricks.net
* updates: mirror.atlantic.net
Available Packages
Name : rakudo
Arch : x86_64
Version : 0.2017.04.2
Release : 1.el7
Size : 3.4 M
Repo : epel/x86_64
Summary : Perl 6 compiler implementation that runs on MoarVM
URL : http://rakudo.org/
License : Artistic 2.0
Description : Rakudo Perl 6, or just Rakudo, is an implementation of the
: Perl 6 language specification. More information about Perl 6 is available
: from <http://perl6.org/>. This package provides a Perl 6 compiler built for
: MoarVM virtual machine.