My understanding is that since this decision occurred at the district court level, it does not have a precedential effect, so I don't think anyone with a pending case can necessarily relax or assume that a similar outcome will be easily obtained.

Note also that in this case, a guilty verdict was entered for the defendant before being vacated by the district court almost a year later. If other CFAA cases have to go through the same process to get a similar outcome, that's better than nothing, but not really something to get excited about from the perspective of someone who has not yet been convicted.

Obviously I'm not privy to the details of weev's legal strategy, but this case didn't seem to help him either in preventing his conviction or in securing his exoneration. His conviction was overturned on unrelated grounds. Perhaps this would've been significant if the venue was not improper. (I haven't read the decision overturning weev's conviction, so it may discuss the applicability of this case regardless).

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re the EFF's amicus brief, amicus briefs are an opportunity for the public to file their comments on the case for the court's consideration. They merely express the author's opinion and hold no value. The EFF opposes the CFAA as written as well as several other bad laws, but that's nothing new.

IANAL.