(trusted boot and TPM are afaik already compromised albeit you need to bring a near rocket scientist)
I will always think physical access is game over whatever 'rocket science' or re-invented old principles people come up with software wise and i'm not sure, but hardware probably too but software is easier to mangle.
And indeed yes, security is layers, layers that make it more difficult, and having many options for layers to choose from that is great.
Also didn't hear about OStree before really, reading up on both for some future project.