I am now in my mid 40s. I started working in tech in the mid-90s. I was ambitious and mainly only worked for or led tech startups. (I did well for myself, so can't complain too much)
When I look back on my career, had I went with my intuition at critical times, instead of what I felt was 'my duty' (or whatever justification I made to deny my intuitive senses), I would clearly be further ahead. In total, I probably wasted several years waiting for people or situations to change for the better, passing up several ultimately better opportunities.
A few times not seeing bad management in a startup where you took options rather than a decent wage would do it too.
I never heard the phrase used to represent opportunity cost and it's not clear that OP intended it in that way.