Do you wear glasses by any chance? I haven't found a decent headphone that doesn't press the frame of my glasses to the point of giving me headache in the first hour.
I have a QuietComfort 15 and a Beyerdynamic DT-770-PRO-32. The Beyerdynamic is bigger and more comfortable on the ears, but puts more pressure so it's it hurts faster. The Bose is smaller and less comfortable on the ears, but lighter, so I can support it a bit longer.