http://www.salon.com/2015/08/14/the_megafauna_massacre_human...
https://en.wikipedia.org/wiki/Australian_megafauna
Add in the damage done during the Agricultural and Industrial Revolutions.
I'm certainly no misanthrope, but we're not Earth's shepherds, we're kind of a scourge.
My personal belief is the goal in life should be to continually improve yourself, as much as possible and in as many ways as possible. Leave the world in a better place than you left it. Enjoy your time while it lasts. Seems like goals worth pursuing to me.