http://www.ntp.org/ntpfaq/NTP-s-refclk.htm
TL;DR Most NTP networks are relying on GPS versus a high precision on-site time keeping device. Break GPS, and you break timekeeping for a wide swath of the worldwide NTP pool. But thems the breaks when you can get access to atomic clocks in space (each GPS satellite carries an atomic clock on board) just by sticking an antenna out the window.
If you require precision time for critical business operations (financial transactions, global database operations), you should be running a precision time source locally at your datacenter; for under $20 an attacker could deny you GPS timing.