Lisp does not come from lambda calculus. Anonymous functions in Lisp get their LAMBDA name from lambda calculus, that's all. MacCarthy admitted that he didn't even understand lambda calculus properly, which is why early Lisp was dynamically scoped: lambdas didn't capture lexical variables. Whereas lambda calculus is lexical. Lexical scoping was adopted in later Lisp dialects and into Common Lisp, making those dialects retroactively related to lambda calculus. (Emacs Lisp shows the traditional behavior of dynamic scoping; therefore it couldn't be said to be related to lambda calculus.)
Lambda calculus is a formalization of number theory which builds up numbers from functions. An important result is that lambda calculus is Turing complete. It shows that we can boostrap numbers and number theory from almost out of nothing, using Church numerals.
Lisp has never built numbers out of Church numerals; it had ordinary integers.
Also, lambda calculus, typed or not, does not have its own syntax as a data type. It doesn't have symbols. You don't quote a symbol and pass it to a function and so on.
So that's basically it; there is a link between Lisp and lambda calculus due to the use of the word lambda in a related way, and a somewhat stronger link between lexically scoped Lisps (which came later) and lambda calculus.