Most adults have to spend half their waking hours doing work they don't like. If they lose their job they starve, lose their homes and medical care.
It's getting very hard to live in great cities like SF and NYC on a middle class income. People waste hundreds of hours a year commuting.
Most computers are pwned most of the time. Anything you connect to the internet can be read by determined bad actors.
Burning fossil fuels will probably cause a climate disaster that will put great cities underwater and create food shortages.
Chemicals in our environment are subtly affecting human brains, and catastrophically affecting certain animals like bees and frogs.
Most items in your grocery store are bad for you.
Politics is getting more extreme and divisive. Few politicians even talk about what policies would be best for the people.
One might have thought that everyone having access to all the world's information through pocket supercomputers would make the world smarter. But clickbait journalism, advertising and gamification are filling people's minds with crap and destroying their ability to focus.
Solving 1% of any of these would be a great achievement.
