I don't know what's the definition of "full" here, but I'd guess they leave the middle back seat empty. 3*18 is still 54 so there's clearly some profit to be made.
oh, that's a good point -- i was forgetting they can pair up 4 different paying customers. i think it must be rare though -- i see full ubers and full lyfts fairly often, but i've only ever seen 2 couples (& it's only $1 more for a pair).