Basically, there's nothing preventing Google themselves from looking at your Docs data in cleartext. And that's bad for corps who want total privacy.
There are a number of "shadow IT" single-admin Quip instances popping up both in systems I'm aware of and those I hear about from other folks, so I'm guessing it's easy to administer. I know it works without Internet connectivity because I saw someone install it in an environment that intentionally has no access.
I've always wanted Google Docs on prem so if Quip is it, that's interesting in itself especially for the security reasons. But, Google has incredibly stringent controls around user data after a particular press-involved incident involving an SRE, so while the paranoia of possibilities is well-founded, in practice they'd need a damned good reason (like a critical failure in the product) to even look. They can, and do, walk employees for getting this stuff wrong.
So theoretically, yes (good security mind), practically, not likely.
So what's the real selling point, then? Like I said it seems like a hybrid of Google Docs and Google Wave.