Particularly if someone is specifically targeting 1password, which they (almost by definition) already would be. It'd just be a single patch to the exploit and you're back in business. Well, okay, obviously that's an oversimplification, but it wouldn't do you much good regardless.
Not necessarily. Malware only requires privilege if it is violating a security policy. There are a variety of attacks in which a process executing as a user is able to access resources controlled by other processes which are executing as the same user.