Prejudices have a prejudiced opinion applied to them. That snarling dog? It may not bite you, but it's rational to be prejudiced towards believing it may harm you. Though it may often be wrong, it proves valuable in the long run. The same goes for the person with a knife out, glaring at you, looking drunk. It could be totally harmless, but it may not be. By all means, go into the dark alley with them if you are wholly against prejudice.
Unless, of course, they're never examined. They can be wrong or detrimental just like anything else. But broken down, all rational behavior towards anything alive is effectively prejudice, because you can't have sufficient knowledge to predict it perfectly.