Digital music can't simulate having a physical album cover, an e-ink screen won't ever be similar to a printed page, no music encoding will physically prevent loudness-wars mastering the way a vinyl record will (the needle would just jump out of the track), no printer will ever be able to fool someone into thinking a document was written on a typewriter.

You can tell the difference if a piece of mail was signed by a human with a pen instead of a printer, and it means something.

The limitations of analog media are very often their strengths, especially in corner cases. The limitations of a medium are often a significant driver for the creative process and losing them or approximating them makes lots of things worse.

Normally people (morally) opposed to analog media spout just as much pseudoscience in defense of their position. (normally people arguing about such things on the Internet are idiots anyway)