I think it's the wrong question. Sure, I'd love to work on the hot new app that everybody has in their pocket and can't live without until next week.
But more than that, I want to work with as many smart people and as few assholes as possible. I've found both groups in startups and enterprise. I also want to make good money, and I want to feel supported in my career development.
The rest, as they say, are implementation details.