I disagree with these points on some general levels, even though for this particular product at this particular price point I can see the raionale somewhat:
1) Consumers might be moving away from desktops, but I don't know that creators are so much yet. However I think that's a moot point - desktop, laptop, tablet, whatever. It's not about form factor it's about computing power and it wouldn't surprise me if the latest iPad Pro or even top-end smartphone had the computing power to do these calculations locally.
2) My 3D Printing Systems UP Mini does the heavy lifting on my local PC and then sends that data off to the printer where the printer stores it in memory. Once the print job is sent off and the printer starts going, there's no longer any need for the PC - you can shut the PC down and leave the printer going.
3) Easily solved with a local Wi-Fi connection. Printers (the paper kind) have had this problem solved for ages now. There was no complicated setup for my cheap printer with Wi-Fi; my desktop just found it.
4) Job queue time may vary sure, but once it's sent to the printer it shouldn't matter.
5) This isn't all-or-nothing. What's stopping this from being an optional feature?
"Now that my 3D printer is driven from the cloud...." That doesn't preclude core functionality being available locally. It does mean that if this start-up doesn't succeed, you'll be left with an expensive paperweight until someone writes open backend firmware.
I really love the idea of this product and I can see how cloud connection can be a real enabler (look at what it's done for voice recognition on low-power devices, for example). I'm just really sceptical of this type of cloud-connected device as a general good thing for consumers - there are both good and bad sides to this. We really do need to be asking these questions and getting proper answers and assurances that as consumers we're getting something that's of benefit to us and that we won't be abandoned.